How Vitamin D Supports Immunity

on May 25, 2020

Vitamin D & How it Works

Vitamin D is an important compound for mediating multiple biochemical reactions in the body. What’s interesting about vitamin D is that it acts more like a hormone.

In fact, all of our cells have vitamin D receptors, which is not the case for other molecules.

The process of producing vitamin D is fascinating and involves multi-step physiology that starts at the level of the skin.

Step 1 –  when the body synthesizes cholesterol, it will get converted at the skin level by a chemical reaction that involves sunlight exposure (i.e., photons).

Step 2 –  once the cholesterol is transformed into the inactive form of vitamin D, the liver will produce a special enzyme that catalyzes a second metabolic reaction.

Step 3 –  finally, the kidneys release an enzyme to produce the active form of vitamin D, which is known as 1,25-dihydroxycholecalciferol.


The health benefits of vitamin D

  • Increases bone mineral density
Bone mineral density gradually decreases as we age. This process is physiological, and it’s exacerbated by a sedentary lifestyle, poor dietary choices, and vitamin D deficiency.
Low bone mineral density can lead to a condition known as osteoporosis, which is characterized by fragile bones and frequent fractures.
Fortunately, vitamin D supplements improve calcium and phosphate metabolism to optimize bone mineralization and decrease the risk of osteoporosis.


  • Facilitates hormonal regulation
Many hormones interact with each other via a common feedback loop, including insulin, growth hormones, and vitamin D.
    • Post-menopausal symptoms
    • Calcium metabolism
    • Blood sugar levels.


  • Optimizes the function of the immune system
Vitamin D is a crucial compound for the regular function of the immune system, as it exerts anti-inflammatory and immunomodulating properties that keep immune reactions in check.
Additionally, vitamin D proved to be a booster of T-cell and macrophage activity to efficiently eradicate any foreign pathogens.
In a 2011 paper, scientists analyzed the effectiveness of vitamin D on the immune system and found that low levels of this compound in the bloodstream increases the risk of infections and immune-related maladies.
The lungs are the most susceptible organs to vitamin D deficiency in terms of immune function. You see, when researchers observed the effects of low vitamin D serum levels, they found that patients had a higher risk of developing asthma, chronic obstructive pulmonary disease (COPD), and respiratory infections.


These findings suggest that vitamin D plays a major role in the innate and specific immune system.



Vitamin D offers a myriad of health benefits for the body that should not be taken for granted. Unfortunately, many people suffer from vitamin D deficiency without even realizing it, which leads to several health problems with unknown origins.

The most effective method to reverse and/or prevent vitamin D deficiency is by integrating dietary supplements into your daily routine.

We, at Nature-Leaf, offer the highest quality vitamin D mixed with other immune-boosting substances to make the most effective immunomodulating supplement in the market.

If you want to find out more, please visit this page for more information.



This blog post is not intended to diagnose, treat, cure or prevent any disease. The views and nutritional advice expressed are not intended for the purpose of providing medical advice. Please always consult your health care provider if you are experiencing any medical conditions. All content on this page has been thoroughly reviewed. Nevertheless, no liability can be accepted for the completeness and accuracy of the information.